butabarbital decreases effects of sufentanil SL by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Watch Intently. Coadministration of CYP3A4 inducers may perhaps minimize sufentanil ranges and efficacy, perhaps precipitating withdrawal syndrome in sufferers which have created physical dependence to sufentanil. Discontinuation of concomitantly used CYP3A4 inducers might increase sufentanil plasma focus.
butabarbital will lower the extent or impact of carvedilol by influencing hepatic enzyme CYP2C9/ten metabolism. Use Warning/Check.
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butabarbital will minimize the level or outcome of felodipine by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
There isn't any sufficient reports in Females for analyzing toddler risk when utilizing this medication throughout breastfeeding. Weigh the probable Rewards towards the potential risks right before getting this medication even though breastfeeding.
butabarbital will lessen the extent or influence of nelfinavir by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
butabarbital will lower the extent or effect of estrogens conjugated artificial by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
Exceptions to this monograph are discussed in further more element in different drug interaction monographs. Think about here therapy modification
Pupils might grant their mothers and fathers proxy use of things in their student report. With no proxy accessibility, mother and father might be struggling to view or shell out charges.
75 mg for guys who also are receiving other CNS depressants. No these kinds of dose change is recommended for Females. Prevent use with other CNS depressants at bedtime; prevent use with Liquor. Consider therapy modification
butabarbital will decrease the extent or effect of armodafinil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Unknown.
butabarbital will reduce the level or effect of quinine by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Unidentified.
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butabarbital will boost the stage or result of clopidogrel by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep track of.
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